Sildenafil Citrate: A Look Inside

Sildenafil citrate, or simply Sildenafil, is by far the most widely used remedy for getting rid of erectile dysfunction, which is the active ingredient of Pfizer’s drug Viagra and its numerous generics. It is an artificially synthesized by the physicians chemical substance, which was originally intended to be used against pulmonary arterial hypertension and alpine edema of the lungs. However, in the course of clinical studies it turned out that the new drug was most effective for relieving men from problems with potency.

The action of this medication is based on relaxation and, accordingly, the expansion of blood vessels. Most strongly after taking this substance, the vessels in the penis dilate, which is accompanied by an increased flow of blood to this organ, in particular, to the cavernous bodies. The result of this is the formation of a strong erection. However, Sildenafil has a positive effect not only on the strength of the erection, but also on its duration: this medicine effectively helps in the fight against premature ejaculation, and also increases the number of sexual acts that follow one after another.
Sildenafil citrate inhibits the enzyme PDE-5 and helps to increase the level of nitric oxide in the male body, which causes its vasodilating effect.

How To Use Sildenafil Citrate Tablets?

Sildenafil is produced in tablets with a content of 25 to 100 mg. Sildenafil 100 mg is suitable for curing advanced potency disorders, 50 mg – for use by patients who experience failures in bed sometimes, and 25 mg – for those who are at risk of inadequate erections due to fatigue, stress, or fear of a new partner. The most common starting dose is 50 mg.

If you don’t know your condition well, fear that you will harm your body or can’t decide which dosage option is appropriate for you and face the question “how much Sildenafil Citrate should I take?”, you should consult an urologist and pass a medical examination. The doctor will diagnose you and, if necessary, give you a prescription for Viagra. Nevertheless, now in many countries it is officially allowed to sell Sildenafil without a prescription, especially in online pharmacies.

Regardless of the dosage, Sildenafil tablets must be taken approximately one hour before sex. Time of onset of the effect varies in different men, because there are two identical organisms simply don’t exist. If you have eaten a lot before swallowing the pill, its absorption into the blood flow slows down, and the effect may be weakened.
It should be noted that this med is prohibited for patients with diseases of heart and blood vessels, because it may reduce or increase your systolic blood pressure and harm your organism. Also, Sildenafil is not recommended to be taken by men with anatomical deformations of the penis, with a tendency to priapism, diseases of the retina, not cured sexually transmitted diseases. Before taking this med see warnings in the instruction manual, this is really important in order not to worsen your condition.
In addition to Viagra and its analogues, Sildenafil is also used as the main active substance in a drug for the treatment of pulmonary arterial hypertension (lack of blood flow in the lungs) named Revatio, but currently this is a much less known application of Sildenafil.

Most common side effects of Sildenafil, according to customers’ report, are distortion of color perception, heart palpitations, reddening of cheeks, headache, nasal congestion, nausea, dizziness, sometimes – upset stomach, back pain, chest pain. In many patients, these unpleasant feelings are expressed quite strongly, which causes doctors to seek a replacement for Viagra. However, in the next 5-10 years, the pharmaceutical market is unlikely to be shocked by the appearance of a new drug, similar in effectiveness to Sildenafil and not having these side effects. All other successfully used today medicines for treatment of impotence are PDE-5 inhibitors, including also a rather popular, but much weaker acting Cialis (its active substance is Tadalafil). When the medicine keeps its top positions for twenty years, as it happened with Sildenafil, one can talk about its relative indispensability, because modern developed medicine very quickly finds better options, if they exist. So for the time being, men will have to put up with the deficiencies of Sildenafil, comforting themselves that scientists have not yet come up with a stronger drug against such an unpleasant condition as erectile dysfunction.

by admin